A novel association between platelet filamin A and soluble N-ethylmaleimide sensitive factor attachment proteins regulates granule secretion

BACKGROUND AND OBJECTIVE: The molecular mechanisms that underpin platelet granule secretion remain poorly defined. Filamin A (FLNA) is an actin-crosslinking and signaling scaffold protein whose role in granule exocytosis has not been explored despite evidence that FLNA gene mutations confer platelet...

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Detalles Bibliográficos
Autores principales: Golla, Kalyan, Paul, Manoj, Lengyell, Tess C., Simpson, Elizabeth M., Falet, Hervé, Kim, Hugh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394388/
https://www.ncbi.nlm.nih.gov/pubmed/37538498
http://dx.doi.org/10.1016/j.rpth.2022.100019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394388/
https://www.ncbi.nlm.nih.gov/pubmed/37538498
http://dx.doi.org/10.1016/j.rpth.2022.100019

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