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Stepwise in vitro screening of MMV pathogen box compounds against Plasmodium falciparum to identify potent antimalarial candidates

Development of resistance to deployed antimalarial drugs is inevitable and needs prompt and continuous discovery of novel candidate drugs. Therefore, the antimalarial activity of 125 compounds from the Medicine for Malaria Ventures (MMV) pathogen box was determined. Combining standard IC(50) and nor...

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Detalles Bibliográficos
Autores principales: Mbye, Haddijatou, Bojang, Fatoumata, Jaiteh, Fatou Kene, Jawara, Aminata, Njie, Bekai, Correa, Simon, D'Alessandro, Umberto, Amambua-Ngwa, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394470/
https://www.ncbi.nlm.nih.gov/pubmed/37329848
http://dx.doi.org/10.1016/j.ijpddr.2023.05.005