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Stepwise in vitro screening of MMV pathogen box compounds against Plasmodium falciparum to identify potent antimalarial candidates
Development of resistance to deployed antimalarial drugs is inevitable and needs prompt and continuous discovery of novel candidate drugs. Therefore, the antimalarial activity of 125 compounds from the Medicine for Malaria Ventures (MMV) pathogen box was determined. Combining standard IC(50) and nor...
Autores principales: | Mbye, Haddijatou, Bojang, Fatoumata, Jaiteh, Fatou Kene, Jawara, Aminata, Njie, Bekai, Correa, Simon, D'Alessandro, Umberto, Amambua-Ngwa, Alfred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394470/ https://www.ncbi.nlm.nih.gov/pubmed/37329848 http://dx.doi.org/10.1016/j.ijpddr.2023.05.005 |
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