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Efficacy of combined targeted therapy with PI3K and CDK4/6 or PARP and WEE1 inhibitors in neuroblastoma cell lines

Neuroblastoma (NB), the most frequent solid extracranial tumor in children, is not always cured by current aggressive therapies that have notable adverse effects; therefore, novel treatments are necessary. Phosphoinositide 3-kinase (PI3K) and fibroblast growth factor receptor inhibitors exhibit syne...

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Detalles Bibliográficos
Autores principales: Lukoseviciute, Monika, Holzhauser, Stefan, Pappa, Eleni, Mandal, Tamoghna, Dalianis, Tina, Kostopoulou, Ourania N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394730/
https://www.ncbi.nlm.nih.gov/pubmed/37477144
http://dx.doi.org/10.3892/or.2023.8603