Cargando…
Efficacy of combined targeted therapy with PI3K and CDK4/6 or PARP and WEE1 inhibitors in neuroblastoma cell lines
Neuroblastoma (NB), the most frequent solid extracranial tumor in children, is not always cured by current aggressive therapies that have notable adverse effects; therefore, novel treatments are necessary. Phosphoinositide 3-kinase (PI3K) and fibroblast growth factor receptor inhibitors exhibit syne...
Autores principales: | Lukoseviciute, Monika, Holzhauser, Stefan, Pappa, Eleni, Mandal, Tamoghna, Dalianis, Tina, Kostopoulou, Ourania N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394730/ https://www.ncbi.nlm.nih.gov/pubmed/37477144 http://dx.doi.org/10.3892/or.2023.8603 |
Ejemplares similares
-
Combination of PARP and WEE1 inhibitors in vitro: Potential for use in the treatment of SHH medulloblastoma
por: Lukoseviciute, Monika, et al.
Publicado: (2023) -
Targeted Therapy of HPV Positive and Negative Tonsillar Squamous Cell Carcinoma Cell Lines Reveals Synergy between CDK4/6, PI3K and Sometimes FGFR Inhibitors, but Rarely between PARP and WEE1 Inhibitors
por: Kostopoulou, Ourania N., et al.
Publicado: (2022) -
Targeted Therapy with PI3K, PARP, and WEE1 Inhibitors and Radiotherapy in HPV Positive and Negative Tonsillar Squamous Cell Carcinoma Cell Lines Reveals Synergy while Effects with APR-246 Are Limited
por: Byskata, Karin, et al.
Publicado: (2022) -
Targeting PI3K, FGFR, CDK4/6 Signaling Pathways Together With Cytostatics and Radiotherapy in Two Medulloblastoma Cell Lines
por: Lukoseviciute, Monika, et al.
Publicado: (2021) -
Effects of PI3K and FGFR inhibitors alone and in combination, and with/without cytostatics in childhood neuroblastoma cell lines
por: Holzhauser, Stefan, et al.
Publicado: (2021)