Mutant p53 in head and neck squamous cell carcinoma: Molecular mechanism of gain‑of‑function and targeting therapy (Review)

Head and neck squamous cell carcinoma (HNSCC) is one of the most widespread malignancies worldwide. p53, as a transcription factor, can play its role in tumor suppression by activating the expression of numerous target genes. However, p53 is one of the most commonly mutated genes, which frequently h...

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Detalles Bibliográficos
Autores principales: Li, Minmin, Sun, Dongyuan, Song, Ning, Chen, Xi, Zhang, Xinyue, Zheng, Wentian, Yu, Yang, Han, Chengbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394732/
https://www.ncbi.nlm.nih.gov/pubmed/37449494
http://dx.doi.org/10.3892/or.2023.8599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394732/
https://www.ncbi.nlm.nih.gov/pubmed/37449494
http://dx.doi.org/10.3892/or.2023.8599

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