Polo‑like kinase 1 selective inhibitor BI2536 (dihydropteridinone) disrupts centrosome homeostasis via ATM‑ERK cascade in adrenocortical carcinoma

Adrenocortical carcinoma (ACC) is a rare but malignant tumor. Surgical removal, radiotherapy and combined chemotherapy are commonly used to treat ACC. Despite efforts for several decades, the mortality rate of ACC remains high after treatments. Therefore, identifying a novel therapeutic molecule is...

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Detalles Bibliográficos
Autores principales: Lin, Ruei-Ci, Chao, Yu-Ying, Lien, Wei-Chih, Chang, Huei-Cih, Tsai, Shih-Wei, Wang, Chia-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394735/
https://www.ncbi.nlm.nih.gov/pubmed/37477142
http://dx.doi.org/10.3892/or.2023.8604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394735/
https://www.ncbi.nlm.nih.gov/pubmed/37477142
http://dx.doi.org/10.3892/or.2023.8604

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