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HOXA1 participates in VSMC-to-macrophage-like cell transformation via regulation of NF-κB p65 and KLF4: a potential mechanism of atherosclerosis pathogenesis

BACKGROUND: Macrophage-like transformation of vascular smooth muscle cells (VSMCs) is a risk factor of atherosclerosis (AS) progression. Transcription factor homeobox A1 (HOXA1) plays functional roles in differentiation and development. This study aims to explore the role of HOXA1 in VSMC transforma...

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Detalles Bibliográficos
Autores principales: Han, Zhiyang, Hu, Haidi, Yin, MingZhu, Lin, Yu, Yan, Yan, Han, Peng, Liu, Bing, Jing, Bao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394793/
https://www.ncbi.nlm.nih.gov/pubmed/37528397
http://dx.doi.org/10.1186/s10020-023-00685-8