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HOXA1 participates in VSMC-to-macrophage-like cell transformation via regulation of NF-κB p65 and KLF4: a potential mechanism of atherosclerosis pathogenesis
BACKGROUND: Macrophage-like transformation of vascular smooth muscle cells (VSMCs) is a risk factor of atherosclerosis (AS) progression. Transcription factor homeobox A1 (HOXA1) plays functional roles in differentiation and development. This study aims to explore the role of HOXA1 in VSMC transforma...
Autores principales: | Han, Zhiyang, Hu, Haidi, Yin, MingZhu, Lin, Yu, Yan, Yan, Han, Peng, Liu, Bing, Jing, Bao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394793/ https://www.ncbi.nlm.nih.gov/pubmed/37528397 http://dx.doi.org/10.1186/s10020-023-00685-8 |
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