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HNRNPC promotes collagen fiber alignment and immune evasion in breast cancer via activation of the VIRMA-mediated TFAP2A/DDR1 axis

BACKGROUND: Cancers aggressively reorganize collagen in their microenvironment, leading to the evasion of tumor cells from immune surveillance. However, the biological significance and molecular mechanism of collagen alignment in breast cancer (BC) have not been well established. METHODS: In this st...

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Detalles Bibliográficos
Autores principales: Lian, Bin, Yan, Shuxun, Li, Jiayi, Bai, Zhengyang, Li, Jinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394847/
https://www.ncbi.nlm.nih.gov/pubmed/37528369
http://dx.doi.org/10.1186/s10020-023-00696-5