Calcineurin inhibition protects against dopamine toxicity and attenuates behavioral decline in a Parkinson’s disease model

BACKGROUND: Parkinson’s disease (PD), a highly prevalent neuro-motor disorder is caused due to progressive loss of dopaminergic (DAergic) neurons at substantia nigra region of brain. This leads to depleted dopamine (DA) content at striatum, thus affecting the fine tuning of basal ganglia. In patient...

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Detalles Bibliográficos
Autores principales: Mondal, Rupsha, Banerjee, Chayan, Nandy, Sumangal, Roy, Moumita, Chakraborty, Joy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394860/
https://www.ncbi.nlm.nih.gov/pubmed/37528492
http://dx.doi.org/10.1186/s13578-023-01068-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394860/
https://www.ncbi.nlm.nih.gov/pubmed/37528492
http://dx.doi.org/10.1186/s13578-023-01068-6

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