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Presymptomatic and early pathological features of MAPT-associated frontotemporal lobar degeneration

Early pathological features of frontotemporal lobar degeneration (FTLD) due to MAPT pathogenic variants (FTLD-MAPT) are understudied, since early-stage tissue is rarely available. Here, we report unique pathological data from three presymptomatic/early-stage MAPT variant carriers (FTLD Clinical Deme...

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Detalles Bibliográficos
Autores principales: Giannini, Lucia AA, Mol, Merel O, Rajicic, Ana, van Buuren, Renee, Sarkar, Lana, Arezoumandan, Sanaz, Ohm, Daniel T, Irwin, David J, Rozemuller, Annemieke JM, van Swieten, John C, Seelaar, Harro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394953/
https://www.ncbi.nlm.nih.gov/pubmed/37533060
http://dx.doi.org/10.1186/s40478-023-01588-9