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RGFP966 exerts neuroprotective effect via HDAC3/Nrf2 pathway after surgical brain injury in rats

Histone deacetylase 3 (HDAC3) restores chromatin nucleosomes to a transcriptional repression state, thereby inhibiting gene expression. Studies have found that HDAC3 expression is upregulated in a variety of pathological states of the central nervous system and related to its neurotoxicity. However,...

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Detalles Bibliográficos
Autores principales: Gu, Hai-Ping, Wu, Xiao-Feng, Gong, Ya-Ting, Mu-Yao Wu, Shi, Meng-Ying, Sun, Ya-ming, Dang, Bao-Qi, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395478/
https://www.ncbi.nlm.nih.gov/pubmed/37539293
http://dx.doi.org/10.1016/j.heliyon.2023.e18160