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A new synthetic ultrasound-assisted method for dibenzoepines

In this study, we have developed a new ultrasonic synthesis method of dibenzoepines using olanzapine and quetiapine, which are well-known drugs for the treatment of schizophrenia and bipolar disorder. The method is based on the N-alkylation reaction of the piperazine fragment in tricyclic compounds...

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Detalles Bibliográficos
Autores principales: Jaśkowska, Jolanta, Drabczyk, Anna Karolina, Kułaga, Damian, Zaręba, Przemysław, Majka, Zbigniew, Jodłowski, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395526/
https://www.ncbi.nlm.nih.gov/pubmed/37539205
http://dx.doi.org/10.1016/j.heliyon.2023.e18319