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Search for Inhibitors of Mycobacterium tuberculosis Transketolase in a Series of Sulfo-Substituted Compounds

As a result of the computer screening of a library of sulfo-substituted compounds, molecules capable of binding to the active site of transketolase from Mycobacterium tuberculosis were identified. An experimental verification of the inhibitory activity of the most promising compound, STK045765, agai...

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Detalles Bibliográficos
Autores principales: Gushchina, I. V., Nilov, D. K., Shcherbakova, T. A., Baldin, S. M., Švedas, V. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395774/
https://www.ncbi.nlm.nih.gov/pubmed/37538800
http://dx.doi.org/10.32607/actanaturae.15709