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Characterization of factors that underlie transcriptional silencing in C. elegans oocytes

While it has been appreciated for decades that prophase-arrested oocytes are transcriptionally silenced on a global level, the molecular pathways that promote silencing have remained elusive. Previous work in C. elegans has shown that both topoisomerase II (TOP-2) and condensin II collaborate with t...

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Detalles Bibliográficos
Autores principales: Belew, Mezmur D., Chien, Emilie, Michael, W. Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395837/
https://www.ncbi.nlm.nih.gov/pubmed/37478128
http://dx.doi.org/10.1371/journal.pgen.1010831