Dynamics of TERT regulation via alternative splicing in stem cells and cancer cells

Part of the regulation of telomerase activity includes the alternative splicing (AS) of the catalytic subunit telomerase reverse transcriptase (TERT). Although a therapeutic window for telomerase/TERT inhibition exists between cancer cells and somatic cells, stem cells express TERT and rely on telom...

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Detalles Bibliográficos
Autores principales: Kim, Jeongjin J., Sayed, Mohammed E., Ahn, Alexander, Slusher, Aaron L., Ying, Jeffrey Y., Ludlow, Andrew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395990/
https://www.ncbi.nlm.nih.gov/pubmed/37531400
http://dx.doi.org/10.1371/journal.pone.0289327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10395990/
https://www.ncbi.nlm.nih.gov/pubmed/37531400
http://dx.doi.org/10.1371/journal.pone.0289327

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