Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I

Respiratory complex I, a key enzyme in mammalian metabolism, captures the energy released by reduction of ubiquinone by NADH to drive protons across the inner mitochondrial membrane, generating the proton-motive force for ATP synthesis. Despite remarkable advances in structural knowledge of this com...

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Detalles Bibliográficos
Autores principales: Grba, Daniel N., Chung, Injae, Bridges, Hannah R., Agip, Ahmed-Noor A., Hirst, Judy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396290/
https://www.ncbi.nlm.nih.gov/pubmed/37531432
http://dx.doi.org/10.1126/sciadv.adi1359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396290/
https://www.ncbi.nlm.nih.gov/pubmed/37531432
http://dx.doi.org/10.1126/sciadv.adi1359

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