Cargando…

Local autocrine plasticity signaling in single dendritic spines by insulin-like growth factors

The insulin superfamily of peptides is essential for homeostasis as well as neuronal plasticity, learning, and memory. Here, we show that insulin-like growth factors 1 and 2 (IGF1 and IGF2) are differentially expressed in hippocampal neurons and released in an activity-dependent manner. Using a new...

Descripción completa

Detalles Bibliográficos
Autores principales: Tu, Xun, Jain, Anant, Parra Bueno, Paula, Decker, Helena, Liu, Xiaodan, Yasuda, Ryohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396292/
https://www.ncbi.nlm.nih.gov/pubmed/37531435
http://dx.doi.org/10.1126/sciadv.adg0666