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SUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome

Ubiquitin and ubiquitin-like conjugation cascades consist of dedicated E1, E2, and E3 enzymes with E3s providing substrate specificity. Mass spectrometry–based approaches have enabled the identification of more than 6500 SUMO2/3 target proteins. The limited number of SUMO E3s provides the unique opp...

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Detalles Bibliográficos
Autores principales: Salas-Lloret, Daniel, Jansen, Nicolette S., Nagamalleswari, Easa, van der Meulen, Coen, Gracheva, Ekaterina, de Ru, Arnoud H., Otte, H. Anne Marie, van Veelen, Peter A., Pichler, Andrea, Goedhart, Joachim, Vertegaal, Alfred C.O., González-Prieto, Román
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396300/
https://www.ncbi.nlm.nih.gov/pubmed/37531430
http://dx.doi.org/10.1126/sciadv.adh2073