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PHF8-GLUL axis in lipid deposition and tumor growth of clear cell renal cell carcinoma

For clear cell renal cell carcinoma (ccRCC), lipid deposition plays important roles in the development, metastasis, and drug resistance. However, the molecular mechanisms underlying lipid deposition in ccRCC remain largely unknown. By conducting an unbiased CRISPR-Cas9 screening, we identified the e...

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Detalles Bibliográficos
Autores principales: Peng, Song, Wang, Ze, Tang, Peng, Wang, Shuo, Huang, Yiqiang, Xie, Qiubo, Wang, Yapeng, Tan, Xintao, Tang, Tang, Yan, Xuzhi, Xu, Jing, Lan, Weihua, Wang, Luofu, Zhang, Dianzheng, Wang, Bin, Pan, Tiejun, Qin, Jun, Jiang, Jun, Liu, Qiuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396305/
https://www.ncbi.nlm.nih.gov/pubmed/37531433
http://dx.doi.org/10.1126/sciadv.adf3566