NPRC deletion attenuates cardiac fibrosis in diabetic mice by activating PKA/PKG and inhibiting TGF-β1/Smad pathways

Cardiac fibrosis plays a key role in the progression of diabetic cardiomyopathy (DCM). Previous studies demonstrated the cardioprotective effects of natriuretic peptides. However, the effects of natriuretic peptide receptor C (NPRC) on cardiac fibrosis in DCM remains unknown. Here, we observed that...

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Detalles Bibliográficos
Autores principales: Meng, Linlin, Lu, Yue, Wang, Xinlu, Cheng, Cheng, Xue, Fei, Xie, Lin, Zhang, Yaoyuan, Sui, Wenhai, Zhang, Meng, Zhang, Yun, Zhang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396312/
https://www.ncbi.nlm.nih.gov/pubmed/37531438
http://dx.doi.org/10.1126/sciadv.add4222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396312/
https://www.ncbi.nlm.nih.gov/pubmed/37531438
http://dx.doi.org/10.1126/sciadv.add4222

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