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Cetuximab enhances radiosensitivity of esophageal squamous cell carcinoma cells by G2/M cycle arrest and DNA repair delay through inhibiting p‐EGFR and p‐ERK

BACKGROUND: Although radiotherapy has improved local control in esophageal squamous cell carcinoma (ESCC), a considerable number of patients still experience relapse due to resistance. In this study, we aimed to evaluate the effects of cetuximab on radiosensitivity in two ESCC cell lines (ECA109 and...

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Detalles Bibliográficos
Autores principales: Zhao, Guifang, Feng, Liwen, Ye, Ting, Liu, Yanshen, Fan, Li, Ye, Chengzhi, Chen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396788/
https://www.ncbi.nlm.nih.gov/pubmed/37337933
http://dx.doi.org/10.1111/1759-7714.14995