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2-Oxabicyclo[2.1.1]hexanes as saturated bioisosteres of the ortho-substituted phenyl ring

The ortho-substituted phenyl ring is a basic structural element in chemistry. It is found in more than three hundred drugs and agrochemicals. During the past decade, scientists have tried to replace the phenyl ring in bioactive compounds with saturated bioisosteres to obtain novel patentable structu...

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Detalles Bibliográficos
Autores principales: Denisenko, Aleksandr, Garbuz, Pavel, Voloshchuk, Nataliya M., Holota, Yuliia, Al-Maali, Galeb, Borysko, Petro, Mykhailiuk, Pavel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396955/
https://www.ncbi.nlm.nih.gov/pubmed/37277469
http://dx.doi.org/10.1038/s41557-023-01222-0