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SLC38A2 and glutamine signalling in cDC1s dictate anti-tumour immunity

Cancer cells evade T cell-mediated killing through tumour–immune interactions whose mechanisms are not well understood(1,2). Dendritic cells (DCs), especially type-1 conventional DCs (cDC1s), mediate T cell priming and therapeutic efficacy against tumours(3). DC functions are orchestrated by pattern...

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Detalles Bibliográficos
Autores principales: Guo, Chuansheng, You, Zhiyuan, Shi, Hao, Sun, Yu, Du, Xingrong, Palacios, Gustavo, Guy, Cliff, Yuan, Sujing, Chapman, Nicole M., Lim, Seon Ah, Sun, Xiang, Saravia, Jordy, Rankin, Sherri, Dhungana, Yogesh, Chi, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396969/
https://www.ncbi.nlm.nih.gov/pubmed/37407815
http://dx.doi.org/10.1038/s41586-023-06299-8