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2-Arachidonoylglycerol Attenuates Myocardial Fibrosis in Diabetic Mice Via the TGF-β1/Smad Pathway

PURPOSE: Diabetic cardiomyopathy (DM) is the cause of late cardiac dysfunction in diabetic patients. Myocardial fibrosis is the main pathological mechanism, and it is associated with transforming growth factor-β1(TGF-β1) expression up-regulation. 2-Arachidonoylglycerol (2-AG) is an endogenous cannab...

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Detalles Bibliográficos
Autores principales: Chen, Zhengjie, Zheng, Liangyu, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397148/
https://www.ncbi.nlm.nih.gov/pubmed/35305183
http://dx.doi.org/10.1007/s10557-021-07307-7