Direct inference and control of genetic population structure from RNA sequencing data

RNAseq data can be used to infer genetic variants, yet its use for estimating genetic population structure remains underexplored. Here, we construct a freely available computational tool (RGStraP) to estimate RNAseq-based genetic principal components (RG-PCs) and assess whether RG-PCs can be used to...

Descripción completa

Detalles Bibliográficos
Autores principales: Fachrul, Muhamad, Karkey, Abhilasha, Shakya, Mila, Judd, Louise M., Harshegyi, Taylor, Sim, Kar Seng, Tonks, Susan, Dongol, Sabina, Shrestha, Rajendra, Salim, Agus, Baker, Stephen, Pollard, Andrew J., Khor, Chiea Chuen, Dolecek, Christiane, Basnyat, Buddha, Dunstan, Sarah J., Holt, Kathryn E., Inouye, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397182/
https://www.ncbi.nlm.nih.gov/pubmed/37532769
http://dx.doi.org/10.1038/s42003-023-05171-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397182/
https://www.ncbi.nlm.nih.gov/pubmed/37532769
http://dx.doi.org/10.1038/s42003-023-05171-9

Ejemplares similares