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A new fasciocutaneous flap model identifies a critical role for endothelial Notch signaling in wound healing and flap survival

Flap surgery is a common treatment for severe wounds and a major determinant of surgical outcome. Flap survival and healing depends on adaptation of the local flap vasculature. Using a novel and defined model of fasciocutaneous flap surgery, we demonstrate that the Notch ligand Delta-like 1 (Dll1),...

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Detalles Bibliográficos
Autores principales: Dastagir, Khaled, Gamrekelashvili, Jaba, Dastagir, Nadjib, Limbourg, Anne, Kijas, Dustin, Kapanadze, Tamar, Vogt, Peter M., Limbourg, Florian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397185/
https://www.ncbi.nlm.nih.gov/pubmed/37532879
http://dx.doi.org/10.1038/s41598-023-39722-1