Carcinoma-associated fibroblast-derived lysyl oxidase-rich extracellular vesicles mediate collagen crosslinking and promote epithelial-mesenchymal transition via p-FAK/p-paxillin/YAP signaling

Carcinoma-associated fibroblasts (CAFs) are the main cellular components of the tumor microenvironment and promote cancer progression by modifying the extracellular matrix (ECM). The tumor-associated ECM is characterized by collagen crosslinking catalyzed by lysyl oxidase (LOX). Small extracellular...

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Detalles Bibliográficos
Autores principales: Liu, Xue, Li, Jiao, Yang, Xuesong, Li, Xiaojie, Kong, Jing, Qi, Dongyuan, Zhang, Fuyin, Sun, Bo, Liu, Yuehua, Liu, Tingjiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397209/
https://www.ncbi.nlm.nih.gov/pubmed/37532712
http://dx.doi.org/10.1038/s41368-023-00236-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397209/
https://www.ncbi.nlm.nih.gov/pubmed/37532712
http://dx.doi.org/10.1038/s41368-023-00236-1

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