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Single-cell profiling reveals the trajectory of FOLR2-expressing tumor-associated macrophages to regulatory T cells in the progression of lung adenocarcinoma

An immunosuppressive microenvironment enriched with regulatory CD4(+) T lymphocytes (Tregs) facilitates the progression of lung adenocarcinoma (LUAD). This study aims to investigate the cellular mechanism underlying the formation of the immunosuppressive microenvironment in LUAD. LUAD samples (n = 1...

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Detalles Bibliográficos
Autores principales: Xiang, Chan, Zhang, Min, Shang, Zhanxian, Chen, Shengnan, Zhao, Jikai, Ding, Bowen, Jiang, Dong, Zhu, Qian, Teng, Haohua, Zhu, Lei, Shao, Jinchen, Zhao, Ruiying, Ye, Min, Yu, Yang, Han, Yuchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397223/
https://www.ncbi.nlm.nih.gov/pubmed/37532692
http://dx.doi.org/10.1038/s41419-023-06021-6