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Single-cell profiling reveals the trajectory of FOLR2-expressing tumor-associated macrophages to regulatory T cells in the progression of lung adenocarcinoma
An immunosuppressive microenvironment enriched with regulatory CD4(+) T lymphocytes (Tregs) facilitates the progression of lung adenocarcinoma (LUAD). This study aims to investigate the cellular mechanism underlying the formation of the immunosuppressive microenvironment in LUAD. LUAD samples (n = 1...
Autores principales: | Xiang, Chan, Zhang, Min, Shang, Zhanxian, Chen, Shengnan, Zhao, Jikai, Ding, Bowen, Jiang, Dong, Zhu, Qian, Teng, Haohua, Zhu, Lei, Shao, Jinchen, Zhao, Ruiying, Ye, Min, Yu, Yang, Han, Yuchen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397223/ https://www.ncbi.nlm.nih.gov/pubmed/37532692 http://dx.doi.org/10.1038/s41419-023-06021-6 |
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