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LC–MS/MS-based quantification of tryptophan, kynurenine, and kynurenic acid in human placental, fetal membranes, and umbilical cord samples

Tryptophan breakdown metabolites formed along the kynurenine pathway play a significant role in pregnancy and fetal development. To understand their involvement, it is crucial to quantify the levels of tryptophan (TRP), kynurenine (KYN), and kynurenic acid (KYNA) in relevant biological samples such...

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Detalles Bibliográficos
Autores principales: Pedraz-Petrozzi, Bruno, Marszalek-Grabska, Marta, Kozub, Anna, Szalaj, Klaudia, Trzpil, Alicja, Stachniuk, Anna, Lamadé, Eva Kathrin, Gilles, Maria, Deuschle, Michael, Turski, Waldemar A., Fornal, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397233/
https://www.ncbi.nlm.nih.gov/pubmed/37532780
http://dx.doi.org/10.1038/s41598-023-39774-3