Inosine enhances tumor mitochondrial respiration by inducing Rag GTPases and nascent protein synthesis under nutrient starvation

Metabolic heterogeneity of tumor microenvironment (TME) is a hallmark of cancer and a big barrier to cancer treatment. Cancer cells display diverse capacities to utilize alternative carbon sources, including nucleotides, under poor nutrient circumstances. However, whether and how purine, especially...

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Detalles Bibliográficos
Autores principales: Li, Mei-Xin, Wu, Xiao-Ting, Jing, Wen-Qiang, Hou, Wen-Kui, Hu, Sheng, Yan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397262/
https://www.ncbi.nlm.nih.gov/pubmed/37532694
http://dx.doi.org/10.1038/s41419-023-06017-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397262/
https://www.ncbi.nlm.nih.gov/pubmed/37532694
http://dx.doi.org/10.1038/s41419-023-06017-2

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