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Pediatric T-cell acute lymphoblastic leukemia blast signature and MRD associated immune environment changes defined by single cell transcriptomics analysis

Different driver mutations and/or chromosomal aberrations and dysregulated signaling interactions between leukemia cells and the immune microenvironment have been implicated in the development of T-cell acute lymphoblastic leukemia (T-ALL). To better understand changes in the bone marrow microenviro...

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Detalles Bibliográficos
Autores principales: Bhasin, Swati S., Thomas, Beena E., Summers, Ryan J., Sarkar, Debasree, Mumme, Hope, Pilcher, William, Emam, Mohamed, Raikar, Sunil S., Park, Sunita I., Castellino, Sharon M., Graham, Douglas K., Bhasin, Manoj K., DeRyckere, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397284/
https://www.ncbi.nlm.nih.gov/pubmed/37532715
http://dx.doi.org/10.1038/s41598-023-39152-z