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Pediatric T-cell acute lymphoblastic leukemia blast signature and MRD associated immune environment changes defined by single cell transcriptomics analysis
Different driver mutations and/or chromosomal aberrations and dysregulated signaling interactions between leukemia cells and the immune microenvironment have been implicated in the development of T-cell acute lymphoblastic leukemia (T-ALL). To better understand changes in the bone marrow microenviro...
Autores principales: | Bhasin, Swati S., Thomas, Beena E., Summers, Ryan J., Sarkar, Debasree, Mumme, Hope, Pilcher, William, Emam, Mohamed, Raikar, Sunil S., Park, Sunita I., Castellino, Sharon M., Graham, Douglas K., Bhasin, Manoj K., DeRyckere, Deborah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397284/ https://www.ncbi.nlm.nih.gov/pubmed/37532715 http://dx.doi.org/10.1038/s41598-023-39152-z |
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