Skp2-mediated MLKL degradation confers cisplatin-resistant in non-small cell lung cancer cells

Non-small cell lung cancer (NSCLC) is the most prevalent type of cancer and the leading cause of cancer-related death. Chemotherapeutic resistance is a major obstacle in treating NSCLC patients. Here, we discovered that the E3 ligase Skp2 is overexpressed, accompanied by the downregulation of necrop...

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Detalles Bibliográficos
Autores principales: Zhou, Huiling, Zhou, Li, Guan, Qing, Hou, Xuyang, Wang, Cong, Liu, Lijun, Wang, Jian, Yu, Xinfang, Li, Wei, Liu, Haidan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397346/
https://www.ncbi.nlm.nih.gov/pubmed/37532777
http://dx.doi.org/10.1038/s42003-023-05166-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397346/
https://www.ncbi.nlm.nih.gov/pubmed/37532777
http://dx.doi.org/10.1038/s42003-023-05166-6

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