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Dual epigenetic changes in diabetes mellitus‐associated pancreatic ductal adenocarcinoma correlate with downregulation of E‐cadherin and worsened prognosis

Diabetes mellitus (DM) is a risk factor for pancreatic ductal adenocarcinoma (PDAC) that promotes the promoter methylation of CDH1. It is still unclear whether DM can exert other epigenetic effects, such as altering microRNA (miR) expression, in PDAC. The expression of miR‐100‐5p is known to be chan...

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Detalles Bibliográficos
Autores principales: Hara, Yutaro, Mizukami, Hiroki, Yamazaki, Keisuke, Yamada, Takahiro, Igawa, Akiko, Takeuchi, Yuki, Sasaki, Takanori, Kushibiki, Hanae, Murakami, Kotaro, Kudoh, Kazuhiro, Ishido, Keinosuke, Hakamada, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397378/
https://www.ncbi.nlm.nih.gov/pubmed/37246239
http://dx.doi.org/10.1002/cjp2.326