A Mendelian randomization study for drug repurposing reveals bezafibrate and fenofibric acid as potential osteoporosis treatments

Background: Lipid pathways have been implicated in the pathogenesis of osteoporosis (OP). Lipid-lowering drugs may be used to prevent and treat OP. However, the causal interpretation of results from traditional observational designs is controversial by confounding. We aimed to investigate the causal...

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Detalles Bibliográficos
Autores principales: Li, Xiao-Hua, Pang, Wei-Wei, Zhang, Yue, Liu, Dan-Yang, Yi, Qiao-Rong, Wang, Ning, Zhang, Fu-Rong, Deng, Yun, Chen, Xiang-Ding, Greenbaum, Jonathan, Xiao, Hong-Mei, Deng, Hong-Wen, Tan, Li-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397407/
https://www.ncbi.nlm.nih.gov/pubmed/37547327
http://dx.doi.org/10.3389/fphar.2023.1211302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397407/
https://www.ncbi.nlm.nih.gov/pubmed/37547327
http://dx.doi.org/10.3389/fphar.2023.1211302

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