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A Mendelian randomization study for drug repurposing reveals bezafibrate and fenofibric acid as potential osteoporosis treatments
Background: Lipid pathways have been implicated in the pathogenesis of osteoporosis (OP). Lipid-lowering drugs may be used to prevent and treat OP. However, the causal interpretation of results from traditional observational designs is controversial by confounding. We aimed to investigate the causal...
Autores principales: | Li, Xiao-Hua, Pang, Wei-Wei, Zhang, Yue, Liu, Dan-Yang, Yi, Qiao-Rong, Wang, Ning, Zhang, Fu-Rong, Deng, Yun, Chen, Xiang-Ding, Greenbaum, Jonathan, Xiao, Hong-Mei, Deng, Hong-Wen, Tan, Li-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397407/ https://www.ncbi.nlm.nih.gov/pubmed/37547327 http://dx.doi.org/10.3389/fphar.2023.1211302 |
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