Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2‐positive gastric cancer

BACKGROUND: Trastuzumab is a first‐line targeted therapy for human epidermal growth factor receptor‐2 (HER2)‐positive gastric cancer. However, the inevitable occurrence of acquired trastuzumab resistance limits the drug benefit, and there is currently no effective reversal measure. Existing research...

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Detalles Bibliográficos
Autores principales: Hu, Xingbin, Ma, Zhenfeng, Xu, Beibei, Li, Shulong, Yao, Zhiqi, Liang, Bishan, Wang, Jiao, Liao, Wangjun, Lin, Li, Wang, Chunling, Zheng, Siting, Wu, Qijing, Huang, Qiong, Yu, Le, Wang, Fenghua, Shi, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397568/
https://www.ncbi.nlm.nih.gov/pubmed/37434399
http://dx.doi.org/10.1002/cac2.12459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397568/
https://www.ncbi.nlm.nih.gov/pubmed/37434399
http://dx.doi.org/10.1002/cac2.12459

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