Structural and molecular insight into antibody recognition of dynamic neoepitopes in membrane tethered MUC1 of pancreatic cancer cells and secreted exosomes

Pancreatic cancer is highly metastatic and has poor prognosis, mainly due to delayed detection, often after metastasis has occurred. A novel method to enable early detection and disease intervention is strongly needed. Here we unveil for the first time that pancreatic cancer cells (PANC-1) and secre...

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Detalles Bibliográficos
Autores principales: Wakui, Hajime, Yokoi, Yasuhiro, Horidome, Chieko, Ose, Toyoyuki, Yao, Min, Tanaka, Yoshikazu, Hinou, Hiroshi, Nishimura, Shin-Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398351/
https://www.ncbi.nlm.nih.gov/pubmed/37547453
http://dx.doi.org/10.1039/d3cb00036b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398351/
https://www.ncbi.nlm.nih.gov/pubmed/37547453
http://dx.doi.org/10.1039/d3cb00036b

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