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Structural and molecular insight into antibody recognition of dynamic neoepitopes in membrane tethered MUC1 of pancreatic cancer cells and secreted exosomes
Pancreatic cancer is highly metastatic and has poor prognosis, mainly due to delayed detection, often after metastasis has occurred. A novel method to enable early detection and disease intervention is strongly needed. Here we unveil for the first time that pancreatic cancer cells (PANC-1) and secre...
Autores principales: | Wakui, Hajime, Yokoi, Yasuhiro, Horidome, Chieko, Ose, Toyoyuki, Yao, Min, Tanaka, Yoshikazu, Hinou, Hiroshi, Nishimura, Shin-Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398351/ https://www.ncbi.nlm.nih.gov/pubmed/37547453 http://dx.doi.org/10.1039/d3cb00036b |
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