An anti-glioblastoma gold(i)–NHC complex distorts mitochondrial morphology and bioenergetics to induce tumor growth inhibition

Glioblastoma multiforme (GBM) is the most lethal brain cancer subtype, often advanced by the time of initial diagnosis. Existing treatment modalities including surgery, chemotherapy and radiation have been stymied by recurrence, metastasis, drug resistance and brain targetability. Here, we report a...

Descripción completa

Detalles Bibliográficos
Autores principales: Greif, Charles E., Mertens, R. Tyler, Berger, Gilles, Parkin, Sean, Awuah, Samuel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398352/
https://www.ncbi.nlm.nih.gov/pubmed/37547458
http://dx.doi.org/10.1039/d3cb00051f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398352/
https://www.ncbi.nlm.nih.gov/pubmed/37547458
http://dx.doi.org/10.1039/d3cb00051f

Ejemplares similares