P(1) Glutamine isosteres in the design of inhibitors of 3C/3CL protease of human viruses of the Pisoniviricetes class

Viral infections are one of the leading causes of acute morbidity in humans and much endeavour has been made by the synthetic community for the development of drugs to treat associated diseases. Peptide-based enzyme inhibitors, usually short sequences of three or four residues, are one of the classe...

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Detalles Bibliográficos
Autores principales: Stubbing, Louise A., Hubert, Jonathan G., Bell-Tyrer, Joseph, Hermant, Yann O., Yang, Sung Hyun, McSweeney, Alice M., McKenzie-Goldsmith, Geena M., Ward, Vernon K., Furkert, Daniel P., Brimble, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398354/
https://www.ncbi.nlm.nih.gov/pubmed/37547456
http://dx.doi.org/10.1039/d3cb00075c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398354/
https://www.ncbi.nlm.nih.gov/pubmed/37547456
http://dx.doi.org/10.1039/d3cb00075c

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