The effect of metalation on antimicrobial piscidins imbedded in normal and oxidized lipid bilayers

Metalation of the N-terminal Amino Terminal Cu(ii)- and Ni(ii)-binding (ATCUN) motif may enhance the antimicrobial properties of piscidins. Molecular dynamics simulations of free and nickelated piscidins 1 and 3 (P1 and P3) were performed in 3 : 1 POPC/POPG and 2.6 : 1 : 0.4 POPC/POPG/aldo-PC bilaye...

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Detalles Bibliográficos
Autores principales: Dreab, Ana, Bayse, Craig A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398361/
https://www.ncbi.nlm.nih.gov/pubmed/37547452
http://dx.doi.org/10.1039/d3cb00035d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398361/
https://www.ncbi.nlm.nih.gov/pubmed/37547452
http://dx.doi.org/10.1039/d3cb00035d

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