UPLC-MS/MS method for Icariin and metabolites in whole blood of C57 mice: development, validation, and pharmacokinetics study

Icariin, a Chinese medicinal herb with significant effects on Alzheimer’s disease, lacks pharmacokinetic data in mice. To address this, a UPLC-MS/MS method was developed and validated for quantifying Icariin and its metabolites, Icariside I and Icariside II, in the whole blood of mice. The method pr...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Li, Xiuyun, Li, Na, Mi, Ze, Che, Jinjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398387/
https://www.ncbi.nlm.nih.gov/pubmed/37547333
http://dx.doi.org/10.3389/fphar.2023.1195525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398387/
https://www.ncbi.nlm.nih.gov/pubmed/37547333
http://dx.doi.org/10.3389/fphar.2023.1195525

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