Comparative cardiac effects of antimalarial drug halofantrine with or without concomitant administration of kolanut or fluconazole in healthy volunteers

BACKGROUND: There is rekindled interest in the cardiotoxicity of antimalarial medicines. Halofantrine is associated with QT interval prolongation. Fluconazole and kolanut alter the pharmacokinetics of halofantrine. OBJECTIVES: The study assessed the electrocardiographic changes of concomitant admini...

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Detalles Bibliográficos
Autores principales: Adedapo, Aduragbenro DA, Ojji, Dike B, Adedapo, Kayode S, Kolade, Yetunde, Babalola, Chinedum P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Makerere Medical School 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398509/
https://www.ncbi.nlm.nih.gov/pubmed/37545974
http://dx.doi.org/10.4314/ahs.v23i1.28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398509/
https://www.ncbi.nlm.nih.gov/pubmed/37545974
http://dx.doi.org/10.4314/ahs.v23i1.28

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