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Comparative cardiac effects of antimalarial drug halofantrine with or without concomitant administration of kolanut or fluconazole in healthy volunteers

BACKGROUND: There is rekindled interest in the cardiotoxicity of antimalarial medicines. Halofantrine is associated with QT interval prolongation. Fluconazole and kolanut alter the pharmacokinetics of halofantrine. OBJECTIVES: The study assessed the electrocardiographic changes of concomitant admini...

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Detalles Bibliográficos
Autores principales:	Adedapo, Aduragbenro DA, Ojji, Dike B, Adedapo, Kayode S, Kolade, Yetunde, Babalola, Chinedum P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Makerere Medical School 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398509/ https://www.ncbi.nlm.nih.gov/pubmed/37545974 http://dx.doi.org/10.4314/ahs.v23i1.28

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