Physiologically-based pharmacokinetic modeling for single and multiple dosing regimens of ceftriaxone in healthy and chronic kidney disease populations: a tool for model-informed precision dosing

Introduction: Ceftriaxone is one of commonly prescribed beta-lactam antibiotics with several label and off-label clinical indications. A high fraction of administered dose of ceftriaxone is excreted renally in an unchanged form, and it may accumulate significantly in patients with impaired renal fun...

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Detalles Bibliográficos
Autores principales: Alasmari, Fawaz, Alasmari, Mohammed S., Muwainea, Hussa Mubarak, Alomar, Hatun A., Alasmari, Abdullah F., Alsanea, Sary, Alshamsan, Aws, Rasool, Muhammad F., Alqahtani, Faleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398570/
https://www.ncbi.nlm.nih.gov/pubmed/37547336
http://dx.doi.org/10.3389/fphar.2023.1200828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398570/
https://www.ncbi.nlm.nih.gov/pubmed/37547336
http://dx.doi.org/10.3389/fphar.2023.1200828

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