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Efficacy and safety of ainuovirine versus efavirenz combination therapies with lamivudine/tenofovir disoproxil fumarate for medication of treatment-naïve HIV-1-positive adults: week 48 results of a randomized controlled phase 3 clinical trial followed by an open-label setting until week 96

BACKGROUND: Ainuovirine (ANV) is a new non-nucleoside reverse transcriptase inhibitor (NNRTI), which was initially synthesized in Korea and later further developed in both Korea and China. METHODS: A randomized, double-blind, double-dummy, positive parallel group, non-inferiority, phase 3 trial was...

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Detalles Bibliográficos
Autores principales: Su, Bin, Gao, Guiju, Wang, Min, Lu, Yanqiu, Li, Linghua, Chen, Chen, Chen, Yuanyuan, Song, Chuan, Yu, Fengting, Li, Ying, Liu, Yixin, Luo, Yang, He, Haolan, Cheng, Cong, Xu, Lixia, Zhang, Tong, Sun, Lijun, Liu, An, Xia, Wei, Qin, Yuanyuan, Zhao, Qingxia, Wei, Hongxia, Cai, Weiping, Chen, Yaokai, Zhang, Fujie, Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398592/
https://www.ncbi.nlm.nih.gov/pubmed/37547039
http://dx.doi.org/10.1016/j.lanwpc.2023.100769